Viagra is used for treating Erectile Dysfunction (ED) in men or Assigned Males at Birth (AMAB).
Erectile Dysfunction is the inability of men or AMAB to get and maintain an erection.
Viagra, containing Sildenafil, may interact with other drugs and medical conditions.
This makes learning about drugs not to take with Viagra even more crucial.
Drugs like Nitrates and Antifungals may interact adversely with Viagra and cause consequences.
To avoid the risk of interactions, always talk to your doctor before taking Viagra.
In this article, we will discuss all the drugs not to take with Viagra.
Drugs not to take with Viagra
As stated earlier, Viagra may have adverse interactions with other medicines, such as Nitrates and other PDE5 inhibitors.
Let’s classify the drugs not to take with Viagra.
| Drug Name/ Class | Example(s) | Result of Viagra Interaction |
|---|---|---|
| Nitrates | Nitroglycerin Isosorbide Mononitrate Isosorbide Dinitrate | May enhance Nitrates’ effects |
| Blood pressure (BP) meds | Alpha-blockers (e.g. Prazosin) Angiotensin Receptor blockers (e.g. Losartan) Calcium channel blockers (e.g. Amlodipine) Central Agonists (e.g. Clonide) | May enhance the effects of BP medicines |
| Guanylate Cyclase (GC) stimulators | Riociguat Vericiguat | May increase the effects of GC stimulators |
| Antifungals | Itraconazole Ketoconazole | May trigger side effects of Viagra |
| Other PDE5 inhibitors | Tadalafil Vardenafil Avanafil | May trigger side effects of Viagra |
| Erythromycin | Not Applicable | May trigger side effects of Viagra |
Talk to your doctor in case you are already taking any of the above medicines.
For a comprehensive understanding of the interactions between Viagra and Nitrates, refer to this article – “Can You Take Viagra and Nitroglycerin Together?“.

