Amenorrhea, defined as the absence of menstruation, can be a concerning condition for many women.
It has two categories: Primary and Secondary Amenorrhea.
Genetic abnormalities, structural issues, or hormonal imbalances can cause Primary Amenorrhea.
In contrast, Secondary Amenorrhea is often caused by reproductive or Endocrine disorders, lifestyle factors, or stress.
Below, we have examined the Amenorrhea causes to help address this complex condition.
Primary Amenorrhea Causes
Primary Amenorrhea can occur when menstruation is absent until age 16 and secondary sexual characteristics are absent.
Genetic abnormalities, such as Turner syndrome or Androgen Insensitivity Syndrome, affect the development of reproductive organs, leading to this condition.
Structural anomalies, like Müllerian Agenesis, involve the incomplete formation of the uterus or vagina, interfering with menstruation.
Hypothalamic Amenorrhea is a condition where menstruation ends due to a communication issue between the Hypothalamus and Pituitary gland.
It happens because the body doesn’t produce enough Gonadotropin-Releasing Hormone (GnRH), resulting in low levels of Luteinizing hormone(LH) and Follicle-Stimulating Hormone (FSH) hormones. This causes issues with the ovaries and a lack of Estrogen.
Thorough evaluation and early diagnosis are important in addressing underlying issues causing Primary Amenorrhea.
Are you curious about the symptoms of Hypothalamic Amenorrhea? Read “Hypothalamic Amenorrhea Symptoms: A Comprehensive Guide”

